Alnylam Pharmaceuticals
ABOUT ALNYLAM
Our Science Is Changing the Way Medicine Treats DiseaseTM
Alnylam has led the translation of RNAi (RNA interference) from Nobel Prize-winning discovery into an innovative, entirely new class of medicines. Founded in 2002 by a team of distinguished life sciences leaders, Alnylam’s vision is to harness the potential of RNAi therapeutics to transform the lives of people living with diseases for which there are limited or inadequate treatment options. Our pioneering work has delivered the world’s first and only approved RNAi therapeutics—ONPATTRO® (patisiran) in 2018, GIVLAARI® (givosiran) in 2019, OXLUMO® (lumasiran) in 2020, and AMVUTTRA® (vutrisiran) in 2022. We are advancing a deep pipeline of innovative RNAi-based medicines in four therapeutic areas: genetic medicines, cardio-metabolic diseases, infectious diseases, and central nervous system (CNS) and ocular diseases.

What’s in a Name?
AL-NY-LAM. Our name may not be the easiest to pronounce, but once you learn it, you’ll never forget it. Alnylam is derived from “Alnilam,” the bright center star in the constellation Orion’s belt, which has been used by navigators for thousands of years and symbolizes our passion for discovery.
RNAi Therapeutics—An Innovative New Class of Medicines
Medicines based on RNAi work by “silencing” or disabling the production (“expression”) of the genes that cause specific diseases. In doing so, RNAi therapeutics work “upstream” of most other classes of medicines, such as small molecules and monoclonal antibodies, by targeting the “root” genetic cause of a disease rather than its symptoms. To learn more about our science, click here.
RNAi is the core discovery that forms the therapies Alnylam is developing. It is recognized as a major scientific breakthrough—but how does it work, exactly?

Vision, Mission, and Values
Our Vision - Harnessing a revolution in biology for human health®.
Our Mission - Build a top-tier, global, independent biopharmaceutical company founded on RNAi.
Our Core Values - Commitment to People, Innovation & Discovery, Sense of Urgency, Open Culture, and Passion for Excellence.
CAREERS AT ALNYLAM
Join Our Team and Grow With Us
At Alnylam, we are driven by our mission to translate the Nobel Prize-winning discovery of RNA interference (RNAi) into an innovative, new class of medicines. We’re motivated in this endeavor by the bravery and perseverance of people with unmet medical needs who live with rare and genetic diseases. They are the focus of our efforts, and we exist as a company because of them. That knowledge and commitment to patients is present in everything we do, every day.

At The Forefront of What’s Next
For Patients
Our goal, which is well underway, is to become a world-class biopharmaceutical company that can independently develop and deliver innovative medicines based on RNAi to patients worldwide. We have a deep pipeline of early to late stage investigational therapies, and 2018 marked the approval of our first medicine—the world’s first RNAi therapeutic. Even though we’ve been around since 2002, we’re just getting started!
For Employees
We are growing quickly and hiring across North America, Europe, Asia, and Latin America for a wide variety of roles. We’re seeking smart, passionate, “change the world” kind of people who are ready to say, “challenge accepted.” Our 1,500 (and counting!) employees are building a diverse, equitable, inclusive, and high-performing global organization that celebrates team achievement and recognizes individual contributions.
We’re at the forefront of what’s next for patients, and perhaps your career also.
Search among Alnylam Pharmaceuticals jobs
| Jobs: 1 - 10 of 113 |
Director, New Product Commercialization
Cambridge, Massachusetts
Overview Alnylam is expanding its Pipeline Commercialization capability to match the ambition and complexity of one of the most productive development pipelines in the company's history. The Director, New Pipeline Commercialization will be ...
1d
| Job Type | Full Time |
Associate Director, Advanced Analytics
Cambridge, Massachusetts
Overview Join the Alnylam Commercial Data and Analytics team and help build a product-driven engine that turns data-driven insights into deployed decisions with measurable business impact. As part of Customer Experience and Innovation, you ...
1d
| Job Type | Full Time |
Director, Clinical Quality Risk & Portfolio Oversight
Cambridge, Massachusetts
Director, Clinical Quality Risk & Portfolio Oversight Overview The Director, Clinical Quality Risk & Portfolio Oversight leads enterprise-wide quality intelligence, portfolio risk surveillance, and centralized quality oversight activities a...
1d
| Job Type | Full Time |
Cambridge, Massachusetts
Director, Biostatistics The Director, Biostatistics provides leadership and guidance for large and/or complex late phase clinical development program(s). He/she is responsible for statistical activities including: designing innovative clini...
1d
| Job Type | Full Time |
Associate Director, Clinical Portfolio Technology
Cambridge, Massachusetts
Overview Alnylam isseekinga highly collaborative Associate Director, Clinical Portfolio Technology, to help shape, deliver, and continuously improve technology capabilities that support Clinical Delivery, Portfolio Management, and related D...
1d
| Job Type | Full Time |
Associate Director, Clinical Quality and Continuous Improvement
Cambridge, Massachusetts
Associate Director, Clinical Quality and Continuous Improvement Overview Provides strategic QA oversight across clinical development procedures to ensure compliance with GCP requirements, regulatory expectations, and internal quality standa...
1d
| Job Type | Full Time |
Senior Scientist, Statistical Genetics
Cambridge, Massachusetts
Overview The Alnylam Human Genetics (AHG) team is seeking an exceptional statistical geneticist to join our Analytical Genetics group. The successful candidate will apply cutting-edge methods to analyze genetic data from millions of individ...
2d
| Job Type | Full Time |
Scientist, Genetic Data and Informatics
Cambridge, Massachusetts
Overview The Alnylam Human Genetics (AHG) team is looking for a bioinformatics scientist to join our Data and Informatics group and contribute directly through hands-on data engineering and pipeline development. The successful candidate wil...
2d
| Job Type | Full Time |
US Medical Director, Health System & Payer Engagement
Cambridge, Massachusetts
Position Summary The US Medical Director, Health System & Payer Engagement is a strategic in-house Medical Affairs role responsible for leading end-to-end scientific resource and engagement enablement across Health System and Payer MOSL tea...
2d
| Job Type | Full Time |
Scientist, High-Throughput Biology
Cambridge, Massachusetts
Overview We are seeking a highly motivated scientist to join our High Throughput In Vitro Screening team. This role will lead the in vitro screening workflow to generate high-quality, decision-enabling data across multiple programs. This is...
2d
| Job Type | Full Time |