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Executive Assistant, Commercial Manufacturing & Technical Operations (CMTO)

Vertex Pharmaceuticals Incorporated
paid time off, 401(k)
United States, Massachusetts, Boston
50 Northern Avenue (Show on map)
May 27, 2026

Job Description

General Summary:

The Executive Assistant provides high-impact, independent administrative and operational support to the Senior Vice President of Commercial Manufacturing & Technical Operations (CMTO). Operating in a fast-paced, highly matrixed environment, this role is critical to enabling executive effectiveness through exceptional attention to detail, proactive prioritization, and disciplined execution of complex processes. The Executive Assistant acts as a trusted partner to the SVP, ensuring seamless coordination of priorities, communications, and leadership team operations across a large, cross-functional organization.

Key Duties and Responsibilities:

  • Serve as a strategic administrative partner to the SVP, proactively managing competing priorities, anticipating needs, and ensuring flawless execution of day-to-day operations

  • Own and manage a highly complex, dynamic calendar, aligning shifting business priorities, resolving scheduling conflicts, and optimizing executive time against critical CMTO objectives

  • Coordinate cross-functional leadership activities, including CMTO Leadership Team meetings, extended leadership team engagement, and enterprise-level interactions

  • Drive end-to-end meeting and operational readiness, including agenda development, pre-read coordination, executive briefing materials, note-taking, and follow-up on action items

  • Support CMTO operational rhythms such as talent reviews, business reviews, and planning cycles, ensuring timelines, materials, and stakeholders are aligned

  • Manage confidential communications and decision-support materials, maintaining the highest standards of discretion, accuracy, and professionalism

  • Build and maintain structured administrative processes and systems to improve efficiency, visibility, and consistency across executive workflows

  • Act as a central coordinator across key functions (HR, Finance, Talent Acquisition, Business Operations, etc.), ensuring alignment and follow-through on deliverables

  • Proactively track commitments, deadlines, and action items, following up with stakeholders at all levels to maintain momentum and remove barriers

  • Coordinate complex travel, logistics, and offsite planning, ensuring seamless execution with contingencies proactively addressed

  • Assist with onboarding of new personnel into the CMTO organization and provide guidance to less experienced administrative colleagues

  • Process group purchase orders, invoices, and contracts as needed, and assist with visitor registration and escort

Knowledge and Skills:

  • Exceptional attention to detail with a consistent track record of delivering high-quality, error-free work in high-stakes environments

  • Advanced prioritization and independent judgment, with the ability to assess urgency and importance and adapt quickly as priorities evolve

  • Process-oriented and systems-thinking mindset, with a drive to build structure, improve consistency, and enhance how work gets done

  • Strong business acumen with the ability to understand organizational priorities and align administrative support to business outcomes

  • Executive presence with advanced verbal and written communication skills, including the ability to interact effectively with senior leaders inside and outside the company

  • Ability to handle highly confidential and sensitive information with discretion and integrity

  • Strong collaboration and influencing skills, with the ability to work effectively across functions and levels to drive alignment and results

  • Resilience and adaptability in ambiguous, fast-moving environments with frequently shifting demands

  • Advanced knowledge of Microsoft Office products, including Outlook, PowerPoint, Excel, and Teams

  • Familiarity with enterprise systems such as Workday, SharePoint, and Concur is a plus

  • Experience supporting operational cadences and leadership forums in a complex, matrixed organization is preferred

  • Experience in Manufacturing, Technical Operations, or similarly complex operational organizations is advantageous

Education and Experience:

  • Bachelor's Degree and 5 years of experience providing executive-level administrative support in a complex, matrixed organization, or

  • Associate's Degree and 7 years of experience providing executive-level administrative support in a complex, matrixed organization, or

  • High School Diploma or equivalent and 9 years of experience providing executive-level administrative support in a complex, matrixed organization

Pay Range:

$89,600 - $134,400

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Hybrid

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

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