New

Research Assistant I, Genetics

Brigham and Women's Hospital
United States, Massachusetts, Boston
77 Avenue Louis Pasteur (Show on map)
May 07, 2026
A research technician position is available in the Howard Hughes Laboratory of Dr. Stephen Elledge at Harvard Medical School. The candidate will assist scientists in research focusing on using human cells to gain novel insights into how the human immune system targets cancers (cancer immunology) and how cancers evolve in a tissue-specific manner. Perform standard molecular biology techniques (cloning, site-directed mutagenesis, PCR, and next-generation sequencing). Perform tissue culture work doing plasmid transfection and retroviral infection. Characterize cellular function using biochemistry and cell biology techniques (Western blotting, immunofluorescence, chromatography, flow cytometry, CRISPR, and reporter gene assays). Perform and analyze immunologic assays in cell culture setting to assess B- and T-cell specificity and activity, as well as molecular panning experiments to assess antibody specificity and function. Assist in CRISPR functional genomic screen to identify genes required for the selective survival of tumor cells. Organize and summarize acquired data, using scientific and statistical techniques. QUALIFICATIONS: Bachelor's degree in biology, biochemistry, chemistry, biotechnology or related science field 1-3 years of experience in molecular laboratory preferred SKILLS/ ABILITIES/ COMPETENCIES REQUIRED: Excellent communication skills, both oral and written. Attention to detail. Familiarity with molecular and computational biology. Knowledge of sterile tissue culture technique. Excellent organizational and analytical skills. The Brigham and Women's Hospital, Inc. is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.