New

Human Resources Business Partner Senior Director (Cell & Genetic Research Site)

Vertex Pharmaceuticals Incorporated
paid time off, 401(k)
United States, Massachusetts, Boston
50 Northern Avenue (Show on map)
Jan 22, 2026
Job Description General Summary: We are seeking a strategic, influential, and visionary HR Business Partner Senior Director to lead talent strategies for Vertex's Cell & Genetic Therapies Research site and Research organizations during a transformative era of scientific innovation and organizational growth. This role will serve as a trusted advisor to Research Senior Vice Presidents and Vice Presidents and their leadership teams, shaping organizational design, culture, and workforce strategies that enable cutting-edge discovery and long-term scientific success. Reporting to the Lead HRBP for the Chief Scientific and Global Research organization, this individual will sit on Research leadership teams and play a critical role in driving enterprise-wide HR initiatives and change leadership. As the primary site HRBP for the Jeffrey Leiden Center for Biologics, Cell & Genetic therapies, the Senior Director will provide and ensure the delivery of HR programs and services including leader coaching and consultation, talent development and succession planning, talent acquisition of key positions, employee experience and engagement, and compensation processes. Key Duties and Responsibilities: Lead strategic HR initiativesacross multiple Research domains (Discovery Biology, Chemistry, Translational Research, Computational Sciences) and influence cross-functional areas such as Data Science and Platform Technologies. Serve as akey architect of organizational design and transformation, advising senior leaders on complex change management and culture evolution strategies. Driveenterprise-level workforce planning, including capability mapping, succession planning, and talent acquisition strategies aligned with Vertex's long-range scientific roadmap. Leverage advanced analytics and insightsto inform strategic decisions, challenge assumptions, anddemonstratemeasurable impact on scientific and organizational outcomes. Influence andshape HR strategyat the sub-function level, ensuring alignment with corporate priorities and Researchobjectives. Build andmaintaindeep partnerships with HR Centers of Excellence(Total Rewards, Talent Management, People Experience, Strategic Analytics). Represent HR on Research leadership forums, contributing to strategic planning and decision-making for the sub-function. Ensureflawless execution of critical HR processes(performance management, compensation planning, leadership development) while driving continuous improvement and innovation. Knowledge and Skills: Recognizedexpertin HR strategy and organizational effectiveness, with proven ability to influence senior executives and shape sub-functional priorities. Deep understanding of scientific environments, includingcell and gene therapy,andworkforce capability needs for discovery and translational research. Advancedproficiencyinchange leadership, culture transformation, and strategic workforce planning. Strong business acumenand ability to translate HR strategies into measurable business outcomes. Exceptional communication andinfluencing skills; ability to negotiate and shape opinions of senior leaders. Expertiseinleveragingdata-driven insights andstorytelling to inform decisions and drive transformation. Education and Experience: Bachelor's degree in Human Resourcesor related discipline, or equivalent professional experience. Typically requires 12+ years of progressive HR experience, including significant leadership responsibility and experience in complex, multi-site scientific organizations. Demonstrated success in leading through subordinate managers and influencing sub-function strategy. #LI-LE1 Pay Range: $227,200 - $340,800 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com