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Executive/Senior Director, Global Program Management

GlaxoSmithKline
paid holidays
United States, Pennsylvania, Philadelphia
2929 Walnut Street (Show on map)
Dec 16, 2025
Site Name: Home Worker - USA
Posted Date: Dec 15 2025

Business Introduction
At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people's lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients' needs and have the highest probability of success. We're uniting science, technology, and talent to get ahead of disease together.
Find out more:
Our approach to R&D

Position Summary
As Executive/Senior Director of Program Management for a flagship oncology asset, you will be the driving force behind flawless execution-translating strategy into action and ensuring disciplined delivery of program milestones. You will shape critical decisions by influencing stakeholders through data-driven insights and external perspectives, while fostering a culture of accountability and agility. Your role demands operational rigor, proactive risk management, and the ability to challenge assumptions to accelerate progress without compromising quality or safety.

Key Responsibilities

Acting as the Medicine Development Leader's strategic partner and primary point of contact for the program's Medicine Development Team (MDT), you will oversee a complex, multi-tumor program-integrating clinical development, asset and evidence strategies into a unified vision. You will lead all project management aspects of this high-visibility initiative, ensuring milestone delivery at pace while upholding quality and safety. This involves

Strategic Orchestration and Cross-Functional Leadership.

Integrating clinical, regulatory, CMC, and commercial strategies into a unified program plan; guiding strategic discussions and encouraging diverse viewpoints to reach actionable outcomes; leveraging insights from external experts and benchmarks; and maintaining an overview of systems to identify dependencies and managing complexity.

Demonstrate Critical Thinking

This requires questioning assumptions and exploring new approaches through insightful inquiries; simplifying complex topics into actionable insights for senior leaders; and working with Medicine Development Leaders to optimize asset strategy considering both business and patient needs.

Agility Initiative, and Execution Excellence

An important aspect of this role involves promoting team adaptability to evolving data and priorities, leading scenario planning to minimize disruption while staying aligned with long-term objectives and clearly communicating changes to keep program goals in focus.

Responsibilities include taking ownership of program execution, proactively resolving challenges, leading planning and risk management, tracking progress, identifying opportunities for innovation and efficiency, and accelerating outcomes by streamlining decision-making and removing obstacles.

Stakeholder Engagement and Facilitation Excellence

This role encompasses engaging with senior leaders, governance bodies, external partners, and subject matter experts; leading tailored meetings that enable decisive outcomes; cultivating trusted relationships and influencing through credibility, data-driven insights, and composure; and ensuring program visibility through compelling storytelling and impactful dashboards.

Governance, Communication and Executive Engagement

The role requires facilitating governance interactions and translating complexity into clear, data-driven recommendations; summarizing strategy, risks, and options for decision-making; balancing scientific rigor, operational feasibility, and commercial value; and serving as the single point of accountability for program operations, performance, and budget.

Leadership & Team Development

This role involves people management, therefore mentoring project managers, fostering ownership and high standards; and demonstrating calm and confident leadership to handle ambiguity with discipline and purpose is crucial.

Why You?

Basic Qualification

We are seeking professionals with the following required skills and qualifications to help us achieve our goals:

  • MS, or MBA in Life Sciences or related field
  • 10 + years of drug development in matrix teams, including pharmaceutical consulting.
  • Experienced in project management using PM principles (e.g., PMI/PMBOK), including risk management, planning, execution, scenario analysis, communication, and reporting.
  • Experience at maintaining project plans, budgets, forecasts, and documentation in Planisware.

Preferred Qualification
If you have the following characteristics, it would be a plus:

  • 10+ years in drug development, with at least 5 years in oncology program or portfolio management.
  • A minimum of 3 years' experience in life sciences consulting, specializing in strategic planning and project delivery within the pharmaceutical sector.
  • Proven track record leading large, cross-functional oncology programs (multi-asset or multi-region).
  • Advanced program management tools (Planisware, MS Project, Smartsheet), risk modeling, budget/resource tracking.
  • Soft Skills: Executive presence, stakeholder influence, strategic communication, and ability to navigate ambiguity.
  • Skilled in leading project team meetings.
  • Proficient in preparing for governance reviews to support funding, resources, and project decisions.

What we offer
You will join a purpose-driven organisation committed to uniting science, technology and talent to get ahead of disease together. You will have the chance to lead meaningful work, grow professionally and influence outcomes that matter to patients around the world.

Ready to apply?
If you are motivated to lead complex programmes, develop people, and deliver measurable impact, we encourage you to apply. We welcome applicants from all backgrounds and are committed to inclusion.

The US annual base salary for new hires in this position ranges from $181,500 to $302,500. The US salary ranges take into account a number of factors including work location within the US market, the candidate's skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process.

Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases - to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we're committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at HR.AmericasSC-CS@gsk.com where you can also request a call.

Please note should your inquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receive

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

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