Bioinformatics Operations Intern (Summer 2026)

Position Overview
The intern will be responsible for developing, testing, and implementing tools to detect and quantify DNA damage artifacts-particularly those caused by oxidation and deamination-in next-generation sequencing (NGS) products. This project will require the intern to research and evaluate existing software solutions for artifact detection, as well as adapting or developing new quality control tools as needed to address specific laboratory requirements. A key aspect of this work will be the establishment and validation of optimal thresholds for quality control and artifact filtering. To accomplish these tasks, the intern will work with NGS variant data, quality control metrics, and other data. Close collaboration with laboratory and bioinformatics operations staff will be essential for understanding current workflows. Through this work, the intern will contribute to high standards of data integrity and reliability.

This position is onsite.

Essential Duties
Include, but are not limited to, the following:

• Apply bioinformatics and software engineering skills to create reusable, modular, tested, version-controlled, shared repository oriented, and professional quality informatics, software, and database resources.

• Apply a foundational understanding of genomics, molecular biology, and bioinformatics to inform tool design and strategic approach to quality control problems.

• Utilize basic statistics to understand the impact of a change to bioinformatic algorithms.

• Apply excellent communication and organizational skills to collaborate effectively with the laboratory, bioinformatics and other relevant teams.

• Write, test, and maintain high-quality, reusable code independently and as part of a team, adhering to best practices in software development and data management.

• Suggest and explore alternative or multiple data processing approaches to improve tool performance and adaptability.

• Uphold company mission and values through accountability, innovation, integrity, quality, and teamwork.

• Support and comply with the company's Quality Management System policies and procedures.

• Ability to act with an inclusion mindset and model these behaviors for the organization.

Scheduling requirements:

• Ability to work designated schedule.

Physical requirements

• Ability to work on a mobile device, tablet, or in front of a computer screen and/or perform typing for approximately 85% of a typical working day.

• Ability to use a telephone through a headset.

Minimum Qualifications

• Currently enrolled in a master's/PhD program in Bioinformatics/Computer Science/Bioengineering/Computational Biology or related field.

• Experience with next-generation sequencing (NGS) and genomic technologies.

• Experience with DNA/RNA seq

• Demonstrated proficiency in Python.

• Demonstrated proficiency using Linux/UNIX based systems and shell scripting.

• Demonstrated proficiency with cloud computing (e.g. AWS).

• Demonstrated ability to successfully download, learn, and apply software and database resources for custom analysis and build workflows.

• Demonstrated understanding of scientific computing and programmatic data visualization tools, and of basic statistics.

• Demonstrated familiarity with large-scale data analysis and utilization of high-performance computingsystems and parallel programming.

• Ability to programmatically interact with data.

• Preference giving to candidates with a record of outstanding academic achievement.

• Basic proficiency with Microsoft Word and Excel.

• Demonstrated ability to perform the essential duties of the position with or without accommodation.

• Authorization to work in the United States without sponsorship.