Senior or Principal Bioinformatics Analyst

Job Summary:

Under the direction and guidance of the Director of Informatics Operations (IO), this full-time, benefits-eligible position acts as a Bioinformatics Analyst within IO. One of the primary goals of IO is to facilitate research opportunities within the University of Colorado that leverage the Biobank housed within CCPM. The person in this position will be primarily responsible for building and maintaining both research and clinical pipelines that use data generated through the CCPM Biobank. Responsibilities include but are not limited to the following: leading the creation and maintenance of annual research freezes, providing bioinformatics support of current and future clinical pipelines, preparing documentation of research and clinical pipelines, and preparing scientific presentations and manuscripts.

Supervision Received: Reports to the Director of Informatics Operations (IO)

Supervision Exercised: None

Key Responsibilities:

• Assist in and/or lead the development and implementation of complex analysis pipelines, programming, and data visualization techniques for large genomics and biobank-scale datasets
• Engage in population-scale genomic data analysis using bash scripting and parallel programming in a High-Performance Computing (HPC)/cluster Unix/Linux environment
• Help ensure pipelines accurately and reliably process genetic data for delivery into patients' records for clinical care
• Create and maintain documentation to support informatics pipelines and meet project management delivery schedules

Work Location:

Hybrid - this role is eligible for a hybrid schedule of 3 days per week on campus and as needed for in-person meetings.

Why Join Us:

Join our dynamic team at the Colorado Center for Personalized Medicine (CCPM) at the University of Colorado Anschutz Medical Campus, where we are at the forefront of integrating genetic information to enhance patient care. CCPM is committed to leveraging the unique combination of genetic information derived from its CAP/CLIA biobank lab, and comprehensive electronic health records to improve healthcare outcomes.

Why work for the University?

We have AMAZING benefits and offer exceptional amounts of holiday, vacation, and sick leave! The University of Colorado offers an excellent benefits package including:

• Medical: Multiple plan options
• Dental: Multiple plan options
• Additional Insurance: Disability, Life, Vision
• Retirement 401(a) Plan: Employer contributes 10% of your gross pay
• Paid Time Off: Accruals over the year
• Vacation Days: 22/year (maximum accrual 352 hours)
• Sick Days: 15/year (unlimited maximum accrual)
• Holiday Days: 10/year
• Tuition Benefit: Employees have access to this benefit on all CU campuses
• ECO Pass: Reduced rate RTD Bus and light rail service

There are many additional perks & programs with the CU Advantage.

Diversity and Equity:

The University of Colorado Anschutz Medical Campus is committed to recruiting and supporting a diverse student body, faculty, and administrative staff. The university strives to promote a culture of inclusiveness, respect, communication, and understanding. We encourage applications from women, ethnically minoritized individuals, persons with disabilities, persons within the LGBTQ+ community, and all veterans. In addition, the Anschutz Campus has also been recognized as an Age-Friendly University. The University of Colorado is committed to diversity and equality in education and employment.

Qualifications:

Minimum Qualifications:

Senior Level:

• Bachelor's degree from an accredited college or university in bioinformatics, genetics, or a related field
• Two (2) years of experience using scientific principles and concepts of NGS and GWAS (Illumina) analysis, including experience in the following areas: coding (particularly with R or Python), Unix environments, cloud-computing, relational databases/SQL2*
• 2+ years of experience with Python/R*
• 2+ years of experience working with Unix and/or Linux, including shell scripting*

Principal Level:

• Bachelor's degree from an accredited college or university in bioinformatics, genetics, or a related field
• Four (4) years of experience using scientific principles and concepts of NGS and GWAS (Illumina) analysis, including experience in the following areas: coding (particularly with R or Python), Unix environments, cloud-computing, relational databases/SQL2*
• 4+ years of experience with Python/R*
• 4+ years of experience working with Unix and/or Linux, including shell scripting*

*Experience may be obtained simultaneously

Substitution: A combination of education and related technical/paraprofessional experience may be substituted for the bachelor's degree on a year-for-year basis.

Applicants must meet minimum qualifications at the time of hire.

Preferred Qualifications:

• Master's degree in bioinformatics, genetics, or a related field
• Pipeline development and standard tools for large-scale genomic data inference (e.g., PLINK, PCA, HAIL, GATK)
• Experience with queue management software in high-performance computing environments
• Advanced Perl and/or Python Programming
• Experience with data engineering and data orchestration tools (Nextflow, Snakemake, WDL, etc.)
• Experience developing and deploying containerized workflows (Docker, Singularity, etc.)
• Documented open-source contributions

Knowledge, Skills, and Abilities:

• Ability to communicate effectively, both in writing and orally
• Ability to establish and maintain effective working relationships with employees at all levels throughout the institution
• Demonstrated commitment to advance diversity and inclusion
• Ability to interact with people of varying technical levels to gather requirements and understand existing systems relevant to the challenges at hand
• Ability to interact effectively and respectfully with a team of developers with complementary competencies

How to Apply:

For full consideration, please submit the following document(s):

1. A letter of interest describing relevant job experiences as they relate to listed job qualifications and interest in the position

2. Curriculum vitae / Resume

3. Three to five professional references, including name, address, phone number (mobile number if appropriate), and email address

Questions should be directed to: Emily Casteel, emily.casteel@cuanschutz.edu

Screening of Applications Begins:

Immediately and continues until April 6, 2025.

Anticipated Pay Range:

The starting salary range (or hiring range) for this position has been established as:

Senior Level: $66,346 to $88,904

Principal Level: $76,299 to $102,240

The above salary range (or hiring range) represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting. This position may be eligible for overtime compensation, depending on the level.

Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans, and retirement contributions that add to your bottom line.

Total Compensation Calculator: http://www.cu.edu/node/153125

ADA Statement:

The University will provide reasonable accommodations to applicants with disabilities throughout the employment application process. To request an accommodation pursuant to the Americans with Disabilities Act, please contact the Human Resources ADA Coordinator at hr.adacoordinator@cuanschutz.edu.

Background Check Statement:

The University of Colorado Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students, and visitors. To assist in achieving that goal, we conduct background investigations for all prospective employees.

Vaccination Statement:

CU Anschutz strongly encourages vaccination against the COVID-19 virus and other vaccine-preventable diseases. If you work, visit, or volunteer in healthcare facilities or clinics operated by our affiliated hospital or clinical partners or by CU Anschutz, you will be required to comply with the vaccination and medical surveillance policies of the facilities or clinics where you work, visit, or volunteer, respectively. In addition, if you work in certain research areas or perform certain safety-sensitive job duties, you must enroll in the occupational health medical surveillance program.