2025 Summer Intern - BioAnalytical Sciences

Department Summary

The BioAnalytical Sciences Department, within Development Sciences, uses world-class science to help bring life-changing medicines to patients. We foster an innovative and collaborative environment that values and recognizes a diversity of contributions. You will gain hands-on lab experience, develop professional skills, and have the opportunity to network and learn from professionals in the industry.

This internship position is located in South San Francisco, on-site.

BAS has several groups working on preclinical and clinical programs developing bioanalytical assays with a variety of cutting edge technologies including:

• Ligand-binding Assays: Have you ever wondered how medicines are measured in patient blood or other biological samples collected during a clinical trial? Bioanalytical assays specifically measure the protein drug molecule out of the thousands of different molecules present in blood. You may test a range of antibodies to design and develop Enzyme-Linked ImmunoSorbent Assay (ELISA) or other types of immunoassays and help understand pharmacokinetics (PK), biomarkers, or immunogenicity of a drug being tested in an non clinical (animal) or a clinical study.
• Liquid Chromatography-Mass Spectrometry (LC-MS): Are you interested in detecting drug molecules in biological samples and also characterizing protein structures and sequences? You may design immunoaffinity LC-MS assays based on molecular separations, enzymatic digestions and peptide analysis to help understand PK, biomarkers, metabolism or proteomics for a drug being tested in different biological matrices. Mass spectrometry experience is desired for some advanced projects.
• Cell Biology: Do you want to see how the cells in the body react to drugs or act on the drugs? You may investigate these biological questions using cell-based assays such as cellular internalization and processing, high content imaging, neutralizing antibody (NAb) assay or antibody effector function assays. Your work will consist in the development of cell-based assays and will utilize cell culture and flow cytometry. Confocal imaging expertise is desired for some advanced projects.
• Predictive Sciences: Are you interested in using big data and modeling to understand how drugs act within the body? The predictive sciences group employs forward and reverse translation research to develop in silico and in vitro models to accurately predict the clinical immunogenicity and PK of new drugs. You may use and develop skills such as Immunology, Molecular Biology, cell culture, flow cytometry, confocal microscopy, and scripting (R and/or Python).

The Opportunity

You will lead a project over the course of 12 weeks under the mentorship of an intern manager. For laboratory based positions, you will execute experiments and document your scientific work. You will also attend group meetings and department seminars. Internships will be on-site and most involve laboratory work. It is expected that the interns will showcase their work at the end of the internship to both the department and at a wider Genentech campus event.

Program Highlights

• Intensive 12-weeks full time (40 hours per week) paid internship.

• Program start dates are in May/June (Summer)

• A stipend, based on location, will be provided to help alleviate costs associated with the internship.

• Ownership of challenging and impactful business-critical projects.

• Work with some of the most talented people in the biotechnology industry.

Who You Are

Required Education

You meet one of the following criteria:

• Must be pursuing a Bachelor's degree.

• Must have attained a Bachelor's degree (recent graduates not currently enrolled in a grad program).

• Must be pursuing a Master's degree.

• Must have attained a Master's degree.

• Must be pursuing a PhD.

Required Majors

Biology, Biochemistry, Molecular Biology, Chemistry, Immunology, Pharmaceutical Sciences or related fields.

Required Skills

Experience working in a laboratory.

Preferred Knowledge, Skills, and Qualifications

• Excellent communication, collaboration, and interpersonal skills.

• Complements our culture and the standards that guide our daily behavior & decisions: Integrity, Courage, and Passion.

• ELISA, mass spectrometry, flow cytometry, cell-based assays.

• Able to work on-site for the duration of the internship.

Relocation benefits are not available for this job posting.

The expected salary range for this position based on the primary location of California is $25.00-$45.00 hour. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for paid holiday time off benefits.

Genentech is an equal opportunity employer, and we embrace the increasingly diverse world around us. Genentech prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status and veteran status.